Unraveling The Effects of DICER1 Overexpression on Immune-Related Genes Expression in Mesenchymal Stromal/Stem Cells: Insights for Therapeutic Applications.
Hamid Reza BidkhoriMoein FarshchianHalimeh HasanzadehReza Jafarzadeh EsfehaniReihaneh Alsadat MahmoudianMahdi Moradi MarjanehHoushang Rafat PanahPublished in: Cell journal (2023)
It seems that the ectopic expression of DICER1 in Ad-MSCs is linked to alterations in the expression level of immune-related genes. It is suggested that the manipulation of immune-related pathways in MSCs via the Dicer1 overexpression could facilitate the development of MSCs with distinct immunoregulatory phenotypes.