Electrocardiographic findings in patients with sickle cell disease: A protocol for systematic review and meta-analysis.
Alireza SadeghiEhsan TaherifardHamed MovahedAlireza AhmadkhaniNiloofar Dehdari EbrahimiErfan TaherifardPublished in: Health science reports (2024)
A comprehensive search strategy will be employed across multiple online databases, including PubMed, Embase, Scopus, Web of Science, and Google Scholar, for published and gray literature. Eligible studies will include original articles reporting associations between sociodemographic, clinical, and paraclinical variables and a spectrum of ECG findings in patients with SCD. Independent reviewers will conduct the screening, quality assessment, and data extraction. Quantitative analyses will be performed under a random-effect model using Comprehensive Meta-Analysis software, with subgroup analyses based on SCD status, sickle hemoglobinopathy form, and age group.
Keyphrases
- sickle cell disease
- systematic review
- case control
- meta analyses
- big data
- public health
- electronic health record
- health information
- adverse drug
- randomized controlled trial
- data analysis
- heart rate
- heart failure
- machine learning
- healthcare
- left atrial
- clinical trial
- blood pressure
- study protocol
- phase iii
- mass spectrometry
- open label