"Inactive" ingredients in oral medications.
Daniel RekerSteven M BlumChristoph SteigerKevin E AngerJamie M SommerJohn FanikosGiovanni TraversoPublished in: Science translational medicine (2020)
Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients.