The Effect of Vascular Endothelial Growth Factor on Bone Marrow Mesenchymal Stem Cell Engraftment in Rat Fibrotic Liver upon Transplantation.

Ke YuanChunyou LaiLingling WeiTianhang FengQinyan YangTianying ZhangTao LanYutong YaoGuangming XiangXiaolun Huang

Published in: Stem cells international (2019)

We showed that VEGF promotes the engraftment of BMSCs in liver fibrosis, enhances liver regeneration, and improves liver function. These outcomes may be related to the increasing hepatic sinusoidal endothelium permeability and VCAM-1-increased expression.

Keyphrases

vascular endothelial growth factor
bone marrow
liver fibrosis
mesenchymal stem cells
endothelial cells
stem cells
poor prognosis
oxidative stress
cell therapy
idiopathic pulmonary fibrosis
type diabetes
metabolic syndrome
adipose tissue
umbilical cord
skeletal muscle
long non coding rna