Molecular complex detection in protein interaction networks through reinforcement learning.
Meghana Venkata PalukuriRidhi S PatilEdward M MarcottePublished in: BMC bioinformatics (2023)
Reinforcement learning offers several distinct advantages for community detection, including scalability and knowledge of the walk trajectories defining those communities. Applied to currently available human protein interaction networks, this method had comparable accuracy with other algorithms and notable savings in computational time, and in turn, led to clear predictions of protein function and interactions for several uncharacterized human proteins.