Denosumab-associated jaw bone necrosis in cancer patients: retrospective descriptive case series study.

Ji-Yeon KangSang-Yup KimJae-Seok LimJwa-Young KimGa-Youn JinYeon-Jung LeeEun-Young Lee

Published in: Maxillofacial plastic and reconstructive surgery (2023)

Conservative surgery, along with antibiotic therapy and discontinuation of DMB, was found to be effective in managing the condition. Additional studies are needed to investigate the contribution of steroids and anticancer drugs to jaw bone necrosis, the prevalence of multicenter cases, and whether there is any drug interaction with DMB.

Keyphrases

bone mineral density
cross sectional
postmenopausal women
minimally invasive
soft tissue
coronary artery bypass
body composition
bone loss
stem cells
drug induced
emergency department
clinical trial
surgical site infection
double blind
atrial fibrillation
replacement therapy