A Comprehensive Cancer-Associated MicroRNA Expression Profiling and Proteomic Analysis of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes.
Ganesan JothimaniSurajit PathakSuman DuttaAsim K DuttaroyGanesan JothimaniPublished in: Tissue engineering and regenerative medicine (2022)
Primary human MSCs released miRNAs and growth factors via exosomes that are increasingly implicated in intercellular communications, and hUCMSC-exosomal miRNAs have a critical influence in regulating cell death and apoptosis of cancer cells.
Keyphrases
- mesenchymal stem cells
- umbilical cord
- cell death
- endothelial cells
- bone marrow
- induced pluripotent stem cells
- stem cells
- cell therapy
- cell cycle arrest
- oxidative stress
- pluripotent stem cells
- endoplasmic reticulum stress
- genome wide
- dna methylation
- cell proliferation
- signaling pathway
- transcription factor
- cell adhesion