Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells.

Joëlle El HajjEric NguyenQingyuan LiuClaire BouyerEric AdriaenssensGeorge HilalEvelyne Ségal-Bendirdjian

Published in: Molecular cancer (2018)

This study identifies a new way of telomerase regulation through H19's involvement and thereby reveals a new function for this long non-coding RNA that can be targeted for therapeutic purpose.

Keyphrases

long non coding rna
poor prognosis
induced apoptosis
endothelial cells
liver failure
cell cycle arrest
acute myeloid leukemia
bone marrow
genome wide
cancer therapy
endoplasmic reticulum stress
signaling pathway
aortic dissection
pi k akt