Intratumoral PPT1-positive macrophages determine immunosuppressive contexture and immunotherapy response in hepatocellular carcinoma.
Jialei WengShaoqing LiuQiang ZhouWenxin XuMinghao XuDongmei GaoYinghao ShenYong YiYi ShiQiongzhu DongChenhao ZhouNing RenPublished in: Journal for immunotherapy of cancer (2023)
macrophage infiltration is associated with poor prognosis of patients with HCC. Targeting PPT1 may potentiate the efficacy of immunotherapy for HCC.