ALK and EGFR expression by immunohistochemistry are associated with Merkel cell polyomavirus status in Merkel cell carcinoma.

Tuukka VeijaMia KeroVirve KoljonenTom Böhling

Published in: Histopathology (2019)

ALK and EZH2 expression are frequent in MCC and ALK expression correlates to MCV positivity. EGFR positive tumours might respond to EGFR inhibiting treatment.

Keyphrases

poor prognosis
small cell lung cancer
epidermal growth factor receptor
advanced non small cell lung cancer
tyrosine kinase
long non coding rna
binding protein
stem cells
single cell
signaling pathway
mesenchymal stem cells
replacement therapy
long noncoding rna