Unraveling Complexities in the Absorption and Disposition Kinetics of Abiraterone via Iterative PBPK Model Development and Refinement.
Eleanor Jing Yi CheongSheng Yuan ChinZheng Wei NgTing Jian YapErvin Zhi Bin CheongZiteng WangEric Chun Yong ChanPublished in: Clinical pharmacokinetics (2023)
Our systematic development of the abiraterone PBPK model has demonstrated its application for the prospective interrogation of the individual or combined influences of potential interindividual variabilities influencing the systemic exposure of abiraterone.