P63 expression plays a role in developmental rate, embryo size, and local morphogenesis.

Julia C BoughnerMatthijs C van EedeShoshana SpringLisa X YuNasim RostampourR Mark Henkelman

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2018)

The software atlas technique described the p63-/- phenotype as a combination of developmental delay (i.e., heterochrony) and malformation (i.e., pathological shape; failed organogenesis). This study identifies for the first time global and local roles for p63 in prenatal growth and development. Developmental Dynamics 247:779-787, 2018. © 2018 Wiley Periodicals, Inc.

Keyphrases

poor prognosis
pregnant women
single cell
genome wide
dna methylation
binding protein