Study of late toxicity biomarkers of locally advanced head and neck cancer patients treated with radiotherapy plus cisplatin or cetuximab points to the relevance of skin macrophages (TOX-TTCC-2015-01).
Antonio RullanJuan A Marín-JiménezAlicia LozanoOriol BermejoLorena ArribasNuria RuizIsabel LinaresMiren TabernaXavi PérezMaría PlanaMarc OlivaRicard MesíaPublished in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2024)
Angiogenesis and ECM biomarkers did not differ significantly between CRT and ERT. Macrophage markers increased after both treatments and deserve further investigation as predictors of late toxicity in LA-SCCHN patients. [Protocol code: TOX-TTCC-2015-01/Spanish registry of clinical studies (REec): 2015-003012-21/Date of registration: 27/01/2016].
Keyphrases
- locally advanced
- end stage renal disease
- rectal cancer
- squamous cell carcinoma
- neoadjuvant chemotherapy
- radiation therapy
- oxidative stress
- ejection fraction
- newly diagnosed
- chronic kidney disease
- randomized controlled trial
- phase ii study
- adipose tissue
- early stage
- endothelial cells
- clinical trial
- peritoneal dialysis
- wound healing
- oxide nanoparticles