Sex differences in depressive symptoms and tolerability after treatment with selective serotonin reuptake inhibitor antidepressants: Secondary analyses of the GENPOD trial.
Marilia GougoulakiGlyn LewisDavid J NuttTim J PetersNicola J WilesGemma LewisPublished in: Journal of psychopharmacology (Oxford, England) (2021)
Citalopram was not more effective in women compared with men and there was no difference in tolerability. Women and men had similar prognosis after SSRI treatment and similar prognosis regardless of antidepressant class. Findings were unaltered by menopausal status.
Keyphrases
- depressive symptoms
- polycystic ovary syndrome
- open label
- major depressive disorder
- pregnancy outcomes
- middle aged
- phase iii
- clinical trial
- phase ii
- study protocol
- cervical cancer screening
- placebo controlled
- double blind
- breast cancer risk
- randomized controlled trial
- pregnant women
- bipolar disorder
- combination therapy
- replacement therapy
- metabolic syndrome