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Micro-CT and high-field MRI for studying very early post-mortem human fetal anatomy at 8 weeks of gestation.

Audrey LamourouxMaïda CardosoCélia BotteroMathieu GalloMartha DuraesJennifer SalernoMartin M BertrandValérie RigauFlorent FuchsEve MoustyDavid GenevieveGérard SubsolChristophe Goze-BacGuillaume Captier
Published in: Prenatal diagnosis (2023)
PM non-destructive whole-body multimodal micro-imaging: dice micro-CT and HF-MRI allows for PM human fetal anatomy study as early as 8 WG. It paves the way to virtual autopsy in the very early first trimester. Obtaining a precision phenotype, even regarding miscarriage products, allows a reverse phenotyping to select variants of interest in genome-wide analysis, offering potential genetic counseling for bereaved parents.
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