Argininosuccinate synthase 1 and periportal gene expression in sonic hedgehog hepatocellular adenomas.

Jean-Charles NaultGabrielle CouchyStefano CarusoLéa MeunierLaure CaruanaEric LetouzéSandra RebouissouValérie ParadisJulien Calderaro Jessica Zucman-Rossi

Published in: Hepatology (Baltimore, Md.) (2018)

ASS1 is associated with sonic hedgehog activation as part of a periportal program expressed in shHCA, a molecular subgroup defined by INHBE-GLI1 gene fusion. (Hepatology 2018).

Keyphrases

gene expression
dna methylation
quality improvement
genome wide
copy number
randomized controlled trial
single molecule
phase iii
transcription factor
open label