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Serum Iron Overload Activates the SMAD Pathway and Hepcidin Expression of Hepatocytes via SMURF1.

Ning ZhangPengyao YangYanmeng LiQin OuyangFei HouGuixin ZhuBei ZhangJian HuangJi-Dong JiaAnjian Xu
Published in: Journal of clinical and translational hepatology (2024)
SMURF1 can specifically regulate the BMP/SMAD pathway by augmenting the responsiveness of hepatocytes to BMPs during serum iron overload.
Keyphrases
  • iron deficiency
  • epithelial mesenchymal transition
  • transforming growth factor
  • poor prognosis
  • liver injury
  • mesenchymal stem cells
  • drug induced
  • long non coding rna