Dynamic rewiring of the human interactome by interferon signaling.
Craig H KerrMichael A SkinniderDaniel D T AndrewsAngel M MaderoQueenie W T ChanR Greg StaceyNikolay StoynovEric JanLeonard J FosterPublished in: Genome biology (2020)
Our map of the IFN interactome provides a global view of the complex cellular networks activated during the antiviral response, placing IFN-stimulated genes in a functional context, and serves as a framework to understand how these networks are dysregulated in autoimmune or inflammatory disease.