Factors Affecting Metabolic Outcomes Post Bariatric Surgery: Role of Adipose Tissue.
Sara H KeshavjeeKatherine J P SchwengerJitender YadavTimothy D JacksonAllan OkrainecJohane P AllardPublished in: Journal of clinical medicine (2021)
Obesity is an ever-growing public health crisis, and bariatric surgery (BS) has become a valuable tool in ameliorating obesity, along with comorbid conditions such as diabetes, dyslipidemia and hypertension. BS techniques have come a long way, leading to impressive improvements in the health of the majority of patients. Unfortunately, not every patient responds optimally to BS and there is no method that is sufficient to pre-operatively predict who will receive maximum benefit from this surgical intervention. This review focuses on the adipose tissue characteristics and related parameters that may affect outcomes, as well as the potential influences of insulin resistance, BMI, age, psychologic and genetic factors. Understanding the role of these factors may help predict who will benefit the most from BS.
Keyphrases
- insulin resistance
- adipose tissue
- public health
- bariatric surgery
- weight loss
- type diabetes
- high fat diet
- high fat diet induced
- metabolic syndrome
- glycemic control
- end stage renal disease
- skeletal muscle
- polycystic ovary syndrome
- obese patients
- weight gain
- healthcare
- ejection fraction
- newly diagnosed
- randomized controlled trial
- peritoneal dialysis
- body mass index
- prognostic factors
- cardiovascular disease
- chronic kidney disease
- mental health
- gene expression
- genome wide
- patient reported outcomes
- risk assessment
- copy number
- climate change
- health promotion