Safety, efficacy, and operability of a newly developed absorbable adhesion barrier (GM142) in patients with primary rectal cancer scheduled for diverting ileostomy during laparoscopic surgery: Randomized controlled trial.

Jun Watanabe Shigeki Yamaguchi Ichiro TakemasaMasayoshi YasuiYasumitsu HiranoDaisuke NakanoAkio Shiomi Shinya MunakataMasanori NaitoShunsuke TsukamotoAtsushi IshibeYoshiaki KuriuYasutake UchimaShinichiro MoriHideki KanazawaGo WakabayashiTakeshi YamadaMuneaki EzuMasahiko WatanabeYusuke Kinugasa

Published in: Annals of gastroenterological surgery (2022)

The noninferiority of GM142 to conventional film was shown. GM142 showed no major safety issues. The clinical safety profiles of GM142 suggested certain physiological benefits of the gelatin film as an adhesion barrier.

Keyphrases

randomized controlled trial
laparoscopic surgery
rectal cancer
room temperature
study protocol
biofilm formation
squamous cell carcinoma
clinical trial
locally advanced
systematic review
radiation therapy
cell migration
gold nanoparticles
ionic liquid
candida albicans
double blind
meta analyses