Outcomes of SARS-CoV-2 infection in early pregnancy-A systematic review and meta-analysis.

Kenny Alexandra Rodriguez-Wallberg Hanna Pauline NilssonEmelie Bergman RøtheAllan Zhao Prakesh Shantilal Shah Tullio Ghi

Published in: Acta obstetricia et gynecologica Scandinavica (2024)

In this comprehensive systematic review of available evidence, we identified no statistically significant adverse association between SARS-CoV-2 infection in early pregnancy (before 20 weeks of gestation) and fetal, neonatal, or maternal outcomes. However, a 44% increase in miscarriage rate is concerning and further studies of larger sample size are needed to confirm or refute our findings.

Keyphrases

systematic review
gestational age
meta analyses
respiratory syndrome coronavirus
birth weight
emergency department
type diabetes
randomized controlled trial
body mass index
sars cov
case control