Nitrous oxide for the treatment of complex regional pain syndrome: a randomized blinded trial.
Jason HaleJijun XuDong WangFabio Rodriguez-PatarroyoOmer BakalOrkun KopacEce Yamak AltinpullukOzkan OnalJack E BrookerMiguel CruzMarco MaurtuaRuben Agudelo-JimenezDaniel I SesslerAlparslan TuranPublished in: Regional anesthesia and pain medicine (2023)
Compared with air/oxygen, 2 hours of nitrous oxide/oxygen exposure for three sessions did not provide meaningful therapeutic potential for patients with chronic CRPS. Our results do not support using nitrous oxide for the treatment of CRPS.