Thrombectomy versus Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort.
Amrou SarrajGregory W AlbersJordi BlascoJuan F ArenillasMarc RiboAmeer E HassanNatalia Pérez de la OssaTeddy Yuan-Hao WuPere Cardona PortelaMichael G AbrahamMichael ChenLaith MaaliTimothy J KleinigDennis CordatoAdam Nathan WallaceJoanna D SchaafsmaNavdeep SanghaDaniel P GibsonSpiros L BlackburnMercedes De Lera AlfonsoDeep Kiritbhai PujaraFaris ShakerMargy E McCullough-HicksJavier Luis Moreno NegreteArturo RenuJames BeharryCecilia Cappelen-SmithLuis Rodríguez-EsparragozaMarta Olivé-GadeaManuel Requena RuizTareq AlmaghrabiVitor Mendes PereiraClark SittonSheryl Martin-SchildSarah SongHenry MaLeonid ChurilovPeter J MitchellMark W ParsonsAnthony FurlanJames C GrottaGeoffrey A DonnanStephen M DavisBruce C V Campbellnull nullPublished in: Annals of neurology (2022)
Overall, EVT was not associated with improved clinical outcomes in mild strokes due to LVO, and sICH was increased. However, in patients with target mismatch profile, EVT was associated with increased functional independence. Perfusion imaging may be helpful to select mild stroke patients for EVT. ANN NEUROL 2022;92:364-378.