LINC00163 inhibits the invasion and metastasis of gastric cancer cells as a ceRNA by sponging miR-183 to regulate the expression of AKAP12.
Jun ZhangHai-Yan PiaoShuai GuoYue WangTao ZhangZhi-Chao ZhengYan ZhaoPublished in: International journal of clinical oncology (2020)
Our results demonstrated that weak LINC00163 expression in GC can sponge miR-183 to promote AKAP12. We established that the LINC00163/miR-183/AKAP12 axis plays an important role in GC invasion and metastasis and may be a potential biomarker and target for GC treatment.