Forskolin-mediated BeWo cell fusion involves down-regulation of miR-92a-1-5p that targets dysferlin and protein kinase cAMP-activated catalytic subunit alpha.

Richa DubeySudha S MalhotraSatish Kumar Gupta

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)

These observations suggest that miR-92a-1-5p regulates forskolin-mediated BeWo cell fusion and hCG secretion by regulating PKA signaling pathway and dysferlin expression.

Keyphrases

protein kinase
signaling pathway
single cell
cell therapy
poor prognosis
pi k akt
epithelial mesenchymal transition
oxidative stress
cell proliferation
mesenchymal stem cells
induced apoptosis