Benefits in Cardiac Function from a Remote Exercise Program in Children with Obesity.
Savina MannarinoSara SantacesariaIrene RasoMassimo GarbinAndreana PipoloSilvia GhigliaGabriele TaralloAnnalisa De SilvestriNicola LovecchioDaniela LuciniVittoria Carnevale PellinoGiuseppina BernardelliAlessandro GattiVirginia RossiValeria CalcaterraGian Vincenzo ZuccottiPublished in: International journal of environmental research and public health (2023)
Physical activity (PA) is a crucial factor in preventing and treating obesity and related complications. In this one-arm pre-post longitudinal prospective study, we evaluated the effects of a 12-week online supervised training program on cardiac morphology, function and blood pressure (BP) in children with obesity. The training program consisted of three sessions per week, each lasting 60 min. Advanced echocardiographic imaging (tissue Doppler and longitudinal strain analysis) was used to detect subclinical changes in heart function. Categorical variables were described as counts and percentages; quantitative variables as the mean and standard deviation (SD) as they were normally distributed (Shapiro-Wilks test). Pre-post comparisons were made with a paired t -test. A total of 27/38 (71%) enrolled patients (18M/9F, 11 ± 2 years) completed the training protocol and were considered in the analysis. At baseline, no hypertensive patient was noted; all echocardiographic variables were within the normal range. After training, we observed a significant reduction in BP parameters, including systolic BP values and Z-score, diastolic BP values, centiles and Z-score, and mean arterial pressure (all p < 0.05). Significant variations in echocardiographic interventricular septum (IVSd) thickness ( p = 0.011), IVSd Z-score ( p = 0.001), left ventricular (LV) end-diastolic diameter ( p = 0.045), LV posterior wall thickness Z-score ( p = 0.017), and LV global longitudinal strain ( p = 0.016) were detected. No differences in LV diastolic function and right ventricular strain were noted. PA plays a decisive role in improving BP control and has benefits on left ventricle systolic function, representing a strategic approach to limit CV risk. Online exercise could be an excellent method of training in children with obesity.
Keyphrases
- left ventricular
- blood pressure
- cardiac resynchronization therapy
- metabolic syndrome
- insulin resistance
- ejection fraction
- physical activity
- heart failure
- mitral valve
- hypertrophic cardiomyopathy
- weight loss
- left atrial
- aortic stenosis
- acute myocardial infarction
- high fat diet induced
- type diabetes
- weight gain
- young adults
- end stage renal disease
- pulmonary hypertension
- high resolution
- high intensity
- social media
- heart rate
- hypertensive patients
- peritoneal dialysis
- randomized controlled trial
- virtual reality
- machine learning
- skeletal muscle
- blood flow
- health information
- clinical trial
- pulmonary artery
- chronic kidney disease
- adipose tissue
- quality improvement
- resistance training
- aortic valve
- risk factors
- transcatheter aortic valve replacement
- acute coronary syndrome
- peripheral blood
- preterm birth