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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.

Seyed Arad MoghadasiEmmanuel HeilmannSofia N MoraesFiona L KearnsDorothee von LaerRommie Elizabeth AmaroReuben Stewart Harris
Published in: bioRxiv : the preprint server for biology (2022)
Resistance to protease inhibitor drugs, nirmatrelvir (Paxlovid) and ensitrelvir, exists in SARS-CoV-2 variants in the human population.
Keyphrases
  • sars cov
  • copy number
  • respiratory syndrome coronavirus
  • endothelial cells
  • gene expression
  • dna methylation
  • genome wide
  • coronavirus disease