Phase III Randomized Trial of Maintenance Taxanes Versus Surveillance in Women With Advanced Ovarian/Tubal/Peritoneal Cancer: A Gynecologic Oncology Group 0212:NRG Oncology Study.
Larry J CopelandMark F BradyRobert A BurgerWilliam H RodgersHelen Q HuangDavid CellaDavid M O'MalleyDaron G StreetKrishnansu S TewariDavid P BenderRobert T MorrisWilliam J LoweryDavid Scott MillerSummer B DewdneyNick M SpirtosShashikant B LeleSaketh GuntupalliFrederick Rand UelandGretchen E GlaserRobert S MannelPhilip J DiSaiaPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Maintenance therapy with P and PP did not improve OS among patients with newly diagnosed O/tubal/peritoneal cancer, but may modestly increase PFS. GI and neurologic toxicities were more frequent in the taxane treatment arms.