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Prognosis and prediction of antibiotic benefit in adults with clinically diagnosed acute rhinosinusitis: an individual participant data meta-analysis.

Jeroen HooglandToshihiko TakadaMaarten van SmedenMaroeska M RoversAn I de SutterDaniel MerensteinLaurent KaiserHelena LiiraPaul LittleHeiner C BucherKarel G M MoonsJohannes B ReitsmaRoderick P Venekamp
Published in: Diagnostic and prognostic research (2023)
In conclusion, multivariable prediction based on patient demographics and common signs and symptoms did not reliably predict the patient-level probability of cure and antibiotic effect in this IPD-MA. Therefore, these characteristics cannot be expected to reliably distinguish those that do and do not benefit from antibiotics in adults presenting to primary care with ARS.
Keyphrases
  • case report
  • primary care
  • systematic review
  • liver failure
  • electronic health record
  • meta analyses
  • respiratory failure
  • randomized controlled trial
  • drug induced
  • sleep quality
  • artificial intelligence
  • data analysis