A Network Analysis of Depressive Symptoms in the Elderly with Subjective Memory Complaints.
Sunhae KimKounseok LeePublished in: Journal of personalized medicine (2022)
(1) Background: Subjective memory complaints (SMCs) are common among the elderly and are important because they can indicate early cognitive impairment. The factor with the greatest correlation with SMCs is depression. The purpose of this study is to examine depressive symptoms among elderly individuals with SMCs through a network analysis that can analyze disease models between symptoms; (2) Methods: A total of 3489 data collected from elderly individuals in the community were analyzed. The Subjective Memory Complaints Questionnaire and Patient Health Questionnaire-9 were evaluated. For statistical analysis, we investigated the features of the depressive symptoms network, including centrality and clustering; (3) Results: Network analysis of the SMC group showed strong associations in the order of Q1-Q2 (r = 0.499), Q7-Q8 (r = 0.330), and Q1-Q6 (r = 0.239). In terms of centrality index, Q2 was highest in strength and expected influence, followed by Q1 in all of betweenness, strength, and expected influence; (4) Conclusions: The network analysis confirmed that the most important factors in the subjective cognitive decline group were depressed mood and anhedonia, which also had a strong correlation in the network pattern.
Keyphrases
- network analysis
- depressive symptoms
- sleep quality
- cognitive decline
- middle aged
- social support
- community dwelling
- cognitive impairment
- working memory
- healthcare
- mild cognitive impairment
- mental health
- public health
- physical activity
- electronic health record
- bipolar disorder
- high resolution
- mass spectrometry
- rna seq
- risk assessment
- big data
- artificial intelligence
- machine learning
- atomic force microscopy