Spatial and temporal tracking of multi-layered cells sheet using reporter gene imaging with human sodium iodide symporter: a preclinical study using a rat model of myocardial infarction.
Kentaro OtaniTsutomu ZeniyaHidekazu KawashimaTetsuaki MoriguchiAtsushi NakanoChunlei HanShunsuke MurataKunihiro NishimuraKazuhiro KoshinoKenichi YamaharaMasayuki InubushiHidehiro IidaPublished in: European journal of nuclear medicine and molecular imaging (2024)
The reporter gene imaging with hNIS enables the serial tracking and quantitative kinetic analysis of cell sheets transplanted to infarcted hearts.
Keyphrases
- high resolution
- crispr cas
- copy number
- genome wide
- induced apoptosis
- endothelial cells
- cell therapy
- heart failure
- cell cycle arrest
- single cell
- left ventricular
- genome wide identification
- stem cells
- transcription factor
- dna methylation
- induced pluripotent stem cells
- bone marrow
- gene expression
- cell proliferation
- oxidative stress
- highly efficient
- genome wide analysis
- pluripotent stem cells
- ion batteries