Effects of interleukin-6 receptor blockade on allergen-induced airway responses in mild asthmatics.
Joana A RevezLisa M BainRick M WatsonMichelle TowersTina CollinsKieran J KillianPaul M O'ByrneGail M GauvreauJohn W UphamManuel A R FerreiraPublished in: Clinical & translational immunology (2019)
In a small proof-of-concept clinical trial, we found no evidence that a single dose of tocilizumab was able to prevent allergen-induced bronchoconstriction. (Trial registered in the Australian New Zealand Clinical Trials Registry, number ACTRN12614000123640).