Producing a preference-based quality of LIFE measure to quantify the impact of HYPOGLYCAEMIA on people living with diabetes: A mixed-methods research protocol.
Jill CarltonPhilip A PowellDonna RowenMelanie M BroadleyFrançois PouwerProf Jane SpeightSimon R HellerMari-Anne GallMyriam RosilioChristopher J ChildJonathan David CominsRory J McCrimmonBastiaan E De GalanJohn E Braziernull nullPublished in: Diabetic medicine : a journal of the British Diabetic Association (2022)
A mixed-methods, three-stage design is used: (a) Qualitative interviews will inform the draft PROM content. (b) Cognitive debriefing interview data will be used to refine the draft PROM content. The PROM will be administered in a large-scale survey to enable psychometric validation. Final item selection for the PROM will be informed by psychometric performance, translatability assessment and input from stakeholder groups. (c) A classification system will be generated, comprising a reduced number of items from the PROM. A valuation survey will be conducted to derive a value set for the PBM.