Coronavirus Disease 19 (COVID-19) complicated with pneumonia in a patient with rheumatoid arthritis receiving conventional disease-modifying antirheumatic drugs.
Jehun SongSeongmin KangSeung Won ChoiKwang Won SeoSunggun LeeMin Wook SoDoo-Ho LimPublished in: Rheumatology international (2020)
In December 2019, numerous coronavirus disease 2019 (COVID-19) cases were reported in Wuhan, China, which has since spread throughout the world. However, its impact on rheumatoid arthritis (RA) patients is unknown. Herein, we report a case of COVID-19 pneumonia in a 61-year-old female RA patient who was receiving conventional disease-modifying antirheumatic drugs (cDMARDs). The patient presented with a 4-day history of myalgia and febrile sensation. COVID-19 was confirmed by real-time polymerase chain reaction (PCR). Chest X-ray showed increased opacity on the right lower lung area, and C-reactive protein level was slightly elevated. The patient was treated with antiviral agents (lopinavir/ritonavir), and treatment with cDMARDs was discontinued except hydroxychloroquine. Her symptoms and laboratory results gradually improved. Three weeks later, real-time PCR for COVID-19 showed negative conversion, and the patient was discharged without any complications.
Keyphrases
- coronavirus disease
- rheumatoid arthritis
- sars cov
- case report
- respiratory syndrome coronavirus
- disease activity
- end stage renal disease
- interstitial lung disease
- ankylosing spondylitis
- newly diagnosed
- magnetic resonance imaging
- ejection fraction
- chronic kidney disease
- real time pcr
- rheumatoid arthritis patients
- prognostic factors
- high resolution
- intensive care unit
- community acquired pneumonia
- idiopathic pulmonary fibrosis
- replacement therapy