The Efficacy and Safety of PD-1/PD-L1 Inhibitors in Combination with Conventional Therapies for Advanced Solid Tumors: A Meta-Analysis.

Run-Cong NieChong-Bang ZhaoXiao-Wei XiaYing-Shan LuoTing WuZhi-Wei ZhouShu-Qiang YuanYun Wang Yuan-Fang Li

Published in: BioMed research international (2020)

IOCT is a preferable treatment option over PD-1/PD-L1 inhibitor monotherapy and conventional therapy for patients with advanced solid tumors. However, we should note the increased incidence rate of high-grade AEs in IOCT.

Keyphrases

high grade
combination therapy
low grade
risk factors
randomized controlled trial
study protocol