Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis Patients.
Shotaro TakanoKentaro UchidaShintaro ShojiMakoto ItakuraDai IwaseJun AikawaManabu MukaiHiroyuki SekiguchiGen InoueMasashi TakasoPublished in: BioMed research international (2019)
TGFβ-mediated regulation of VEGF expression and VEGF protein production in the SYT of OA patients occurs through both the canonical and noncanonical pathway.
Keyphrases
- vascular endothelial growth factor
- transforming growth factor
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- endothelial cells
- prognostic factors
- epithelial mesenchymal transition
- peritoneal dialysis
- rheumatoid arthritis
- poor prognosis
- patient reported outcomes
- small molecule
- long non coding rna