Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric Acute Respiratory Distress Syndrome Mortality.
Robinder G KhemaniKaushik ParvathaneniNadir YehyaAnoopindar K BhallaNeal J ThomasChristopher J L NewthPublished in: American journal of respiratory and critical care medicine (2019)
Patients with PARDS managed with lower PEEP relative to FiO2 than recommended by the ARDSNet model had higher mortality. Clinical trials targeting PEEP management in PARDS are needed.