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The two faces of synaptic failure in AppNL-G-F knock-in mice.

Amira Latif-HernandezVictor SabanovTariq AhmedKatleen CraessaertsTakashi SaitoTakaomi SaidoDetlef Balschun
Published in: Alzheimer's research & therapy (2020)
Our data reveal a marked impairment of primarily postsynaptic processes at the level of synaptic plasticity but the dominance of a presumably compensatory presynaptic upregulation at the level of elementary miniature synaptic function.
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