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Immunohistochemical Markers of the Epithelial-to-Mesenchymal Transition (EMT) Are Related to Extensive Lymph Nodal Spread, Peritoneal Dissemination, and Poor Prognosis in the Microsatellite-Stable Diffuse Histotype of Gastric Cancer.

Daniele MarrelliLuigi MaranoMaria Raffaella AmbrosioLudovico CarboneLuigi SpagnoliRoberto PetrioliAlessandra OngaroStefania PiccioniDaniele FusarioFranco Roviello
Published in: Cancers (2022)
EMT status, when assessed through immunohistochemistry, identified an aggressive phenotype of MSS diffuse-type tumors with extensive lymph nodal spread, peritoneal dissemination, and worse long-term outcomes.
Keyphrases
  • poor prognosis
  • epithelial mesenchymal transition
  • long non coding rna
  • low grade
  • lymph node
  • neoadjuvant chemotherapy
  • high grade
  • squamous cell carcinoma