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Avelumab Plus Axitinib as First-Line Therapy for Advanced Renal Cell Carcinoma: Long-Term Results from the JAVELIN Renal 100 Phase Ib Trial.

James M G LarkinMototsugu OyaMarcella MartignoniFiona ThistlethwaitePaul NathanMoshe C OrnsteinThomas PowlesKathryn E BeckermannArjun V BalarDavid McDermottSumati GuptaGeorge K PhilipsMichael S GordonHirotsugu UemuraYoshihiko TomitaJing WangElisabete MichelonAlessandra di PietroToni K Choueiri
Published in: The oncologist (2022)
Five-year follow-up for combination treatment with avelumab plus axitinib in previously untreated patients with aRCC showed long-term clinical activity with no new safety signals, supporting use of this regimen within its approved indication in clinical practice (Clinicaltrials.gov NCT02493751).
Keyphrases
  • renal cell carcinoma
  • clinical practice
  • metastatic renal cell carcinoma
  • clinical trial
  • study protocol
  • phase iii
  • randomized controlled trial
  • phase ii
  • combination therapy
  • replacement therapy