Overexpression of KIAA1199, a novel strong hyaluronidase, is a poor prognostic factor in patients with osteosarcoma.

Kan ItoYoshihiro NishidaKunihiro IkutaHiroshi UrakawaHiroshi KoikeTomohisa SakaiJiarui ZhangYoshie ShimoyamaShiro Imagama

Published in: Journal of orthopaedic surgery and research (2021)

Our results showed that high expression of KIAA1199 and HA are both poor prognostic factors in osteosarcoma. KIAA1199 may be a useful marker for distant metastasis and chemoresistance.

Keyphrases

prognostic factors
poor prognosis
lymph node
cell proliferation
transcription factor
hyaluronic acid
recombinant human
cancer stem cells