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Investigation of the role of α-lipoic acid on fatty acids profile, some minerals (zinc, copper, iron) and antioxidant activity against aluminum-induced oxidative stress in the liver of male rats.

Zafer ŞahinAhmet OzkayaOkkes YilmazAbdurrauf YuceMehmet Gunes
Published in: Journal of basic and clinical physiology and pharmacology (2018)
These results indicate that AlCl3 treatment can induce oxidative stress in the liver. LA supplementation has a beneficial effect on the AlCl3-induced alterations such as high lipid peroxidation, Al accumulation, FA profile ratios and mineral concentrations.
Keyphrases
  • fatty acid
  • oxidative stress
  • diabetic rats
  • oxide nanoparticles
  • high glucose
  • dna damage
  • hydrogen peroxide
  • drug induced
  • replacement therapy
  • endoplasmic reticulum stress