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Longitudinal assessment of quality of life, neurocognition, and psychopathology in patients with low-grade glioma on first-line temozolomide: A feasibility study.

Amelie DarlixMaëva MonnierFlorence CastanLouise CoutantMichel FabbroÈve Denis-ChammasMathilde CarrièreNicolas Menjot-de-ChampfleurValérie RigauHugues DuffauEstelle Guerdoux-Ninot
Published in: Neuro-oncology advances (2024)
This prospective study demonstrated the feasibility of an exhaustive and longitudinal evaluation of QoL, neurocognition, and psychological disorders, with high acceptability by patients with DLGG undergoing chemotherapy. First-line temozolomide seems to have limited short-term effects on QoL and neurocognition. These findings must be confirmed in the long term and in a larger cohort.
Keyphrases
  • low grade
  • high grade
  • cross sectional
  • newly diagnosed
  • squamous cell carcinoma
  • locally advanced
  • radiation therapy