Do ω-3 PUFAs affect insulin resistance in a sex-specific manner? A systematic review and meta-analysis of randomized controlled trials.

Kylie A Abbott Tracy L Burrows Rohith N ThotaShamasunder AcharyaManohar L Garg

Published in: The American journal of clinical nutrition (2016)

With this analysis, we provide preliminary evidence of a sex-dependent response of IR to an n-3 PUFA intervention. Additional studies are needed to confirm sex-dependent associations and to elucidate the potential mechanisms that are involved. This trial was registered at www.crd.york.ac.uk/PROSPERO/ as CRD42015017940.

Keyphrases

randomized controlled trial
systematic review
clinical trial
study protocol
phase iii
phase ii
case control
climate change
human health
risk assessment
placebo controlled