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Mesenchymal Stem Cell Exosomes Promote Functional Osteochondral Repair in a Clinically Relevant Porcine Model.

Shipin ZhangKeng Lin WongXiafei RenKristeen Ye Wen TeoHassan AfizahAndre Boon Hwa ChooRuenn Chai LaiSai Kiang LimJames Hoi Po HuiWei Seong Toh
Published in: The American journal of sports medicine (2022)
Our findings provide a robust scientific rationale to support a phase 1/2 clinical trial to test MSC exosomes in patients with osteochondral lesions.
Keyphrases
  • mesenchymal stem cells
  • clinical trial
  • umbilical cord
  • platelet rich plasma
  • bone marrow
  • stem cells
  • cell therapy
  • phase ii
  • open label
  • study protocol
  • double blind
  • randomized controlled trial