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Pharmacological Action and Research Progress of Taraxasterol.

Yu ZhangRamizu BinShaariMohamad Arif Bin Awang NawiAkram Bin HassanCaiyun Cui
Published in: Current pharmaceutical biotechnology (2024)
Primarily sourced from Asteraceae family herbs such as the Dandelion, Taraxasterol is a pentacyclic triterpenoid lauded for its extensive biological functionalities. Its therapeutic potency is demonstrated in various disease models, encompassing enteritis, arthritis, acute hepatic injury, and pneumonia. Scientific literature underscores its anti-inflammatory, antioxidant, and antineoplastic attributes. The primary aim of this study is to thoroughly explore the diseasemodulating mechanisms and effects of taraxasterol. We endeavor to provide an exhaustive review of the experimental subjects, intervention components, distinct action modalities, contributing factors, and protein pathway expressions associated with taraxasterol, systematically represented via diagrams and tables. Such a schematic representation encourages a continued academic dialogue concerning taraxasterol's pharmacological characteristics. This review is envisioned as a practical guide for the selection of experimental subjects and methodologies in prospective research. It is intended to further illuminate taraxasterol's pharmacodynamics, thereby offering theoretical and empirical justification for its clinical application.
Keyphrases
  • anti inflammatory
  • randomized controlled trial
  • systematic review
  • liver failure
  • respiratory failure
  • oxidative stress
  • protein protein
  • medical students
  • mechanical ventilation