The effect of d-cycloserine on brain processing of breathlessness over pulmonary rehabilitation: an experimental medicine study.
Sarah L FinneganOlivia K HarrisonSara BoothAndrea DennisMartyn EzraCatherine J HarmerMari HerigstadBryan GuillaumeThomas E NicholsNajib M RahmanAndrea ReineckeOlivier RenaudKyle T S PattinsonPublished in: ERJ open research (2023)
Although increasing evidence supports therapeutic modulation of NMDA pathways to treat symptoms, we conclude that a phase 3 clinical trial of d-cycloserine would not be worthwhile.