Antioxidant treatment to reduce mortality and serious adverse events in adult surgical patients: A systematic review with meta-analysis and trial sequential analysis.

Sofie S Pedersen Maria Louise Fabritius Emilie Katrine Kongebro Christian Sahlholt Meyhoff

Published in: Acta anaesthesiologica Scandinavica (2020)

We found a 26% relative risk reduction of mortality in surgical patients treated with antioxidants but the quality of evidence supporting our findings is low and influenced by clinical heterogeneity and high risk of systematic- and random errors.

Keyphrases

cardiovascular events
risk factors
study protocol
clinical trial
single cell
patient safety
randomized controlled trial
type diabetes
emergency department
coronary artery disease
phase ii
anti inflammatory
adverse drug
neural network
smoking cessation
data analysis
electronic health record