Effectiveness of revascularisation for the ulcerated foot in patients with diabetes and peripheral artery disease: A systematic review.
Vivienne H ChuterNicolaas SchaperJoseph MillsRobert HinchliffeDavid RussellNobuyoshi AzumaChristian-Alexander BehrendtEdward J BoykoMichael S ConteMisty D HumphriesLee KirkseyKatharine C McGinigleSigrid NikolJoakim NordanstigVincent RoweJos C van den BergMaarit VenermoRobert FitridgePublished in: Diabetes/metabolism research and reviews (2023)
The majority of available evidence for the effectiveness of DR and IR and open and endovascular revascularisation for wound healing and prevention of minor and major amputation and adverse events including mortality in people with diabetes, PAD and tissue loss is inconclusive, and the certainty of evidence is very low. Data from one high quality randomised controlled trial supports the use of open over endovascular revascularisation to prevent a major limb event and death in people with diabetes, infrainguinal disease and tissue loss who have an adequate great saphenous vein available and who are deemed suitable for either approach.
Keyphrases
- peripheral artery disease
- type diabetes
- randomized controlled trial
- minimally invasive
- cardiovascular disease
- wound healing
- systematic review
- glycemic control
- study protocol
- electronic health record
- risk factors
- aortic dissection
- big data
- machine learning
- editorial comment
- insulin resistance
- skeletal muscle
- percutaneous coronary intervention