Randomized, controlled, multi-center phase II study of postoperative enoxaparin treatment for venous thromboembolism prophylaxis in patients undergoing surgery for hepatobiliary-pancreatic malignancies.
Go ShinkeYutaka TakedaYoshiaki OhmuraShogo KobayashiHiroshi WadaOsakuni MorimotoAkira TomokuniJunzo ShimizuTadafumi AsaokaMasahiro TanemuraTakehiro NodaYuichiro DokiHidetoshi EguchiPublished in: Annals of gastroenterological surgery (2024)
The perioperative administration of enoxaparin in hepatobiliary-pancreatic malignancies is feasible and safe. However, further case accumulation and investigation are necessary to assess its potential in reducing the occurrence of VTE.
Keyphrases
- venous thromboembolism
- patients undergoing
- phase ii study
- open label
- direct oral anticoagulants
- placebo controlled
- minimally invasive
- double blind
- risk assessment
- locally advanced
- phase ii
- coronary artery bypass
- phase iii
- cardiac surgery
- combination therapy
- randomized controlled trial
- surgical site infection
- acute coronary syndrome
- coronary artery disease
- rectal cancer
- replacement therapy